Natera, Inc.

NTRAUS

Natera, Inc. is a diagnostics company focused on developing and commercializing a wide array of molecular testing services globally. Its portfolio includes several key offerings: Panorama, a non-invasive prenatal test (NIPT) that screens for chromosomal abnormalities in a fetus using a blood sample from the mother, and also determines zygosity in twin pregnancies. Vistara, designed to identify single-gene disorders by screening for specific single-gene mutations. Horizon, a comprehensive carrier screening test to determine an individual's carrier status for various genetic diseases. Spectrum, utilized during in vitro fertilization (IVF) cycles to detect chromosomal anomalies or inherited genetic conditions. Anora, a miscarriage analysis product that examines fetal chromosomes to help understand the cause of pregnancy loss. Non-invasive paternity testing, which establishes paternity during gestation using blood samples from both the pregnant mother and the alleged father. Beyond reproductive health, Natera also provides specialized tests: Signatera, a sophisticated circulating tumor DNA (ctDNA) technology capable of screening for a generic set of mutations, independent of the individual's specific tumor characteristics. Prospera, a test used to assess and monitor organ transplant rejection. Additionally, the company offers Constellation, a cloud-based software platform that provides laboratory clients with access to Natera's proprietary algorithms and bioinformatics, enabling them to validate and launch their own tests. Natera distributes its products through a direct sales team and an extensive network of approximately 100 laboratory and distribution partners. The company has strategic partnerships, including one with BGI Genomics Co., Ltd. for the development, manufacturing, and commercialization of NGS-based genetic testing assays, and another with Foundation Medicine, Inc. to develop and commercialize personalized circulating tumor DNA monitoring assays. Founded in 2003, Natera, Inc. is headquartered in Austin, Texas. It was formerly known as Gene Security Network, Inc. before changing its name in 2012.

Founded2003IPO year2015As of2026-08-04
Market Cap
$39.36B
Enterprise Value
$38.51B
EV / LTM Revenue
16.7x
EV / NTM Revenue
12.4x
Trading multiples

Enterprise value over trailing (LTM) vs. forward (NTM) fundamentals. Click an LTM cell to chart it.

LTM
trailing
NTM
forward
Revenue
12.4x
Gross Profit
19.0x
EBITDA
Classification
Sector
Healthcare Services
Sub-sector
Diagnostics & Clinical Services
Listing
NTRA
Country
US
Historical valuation & fundamentals

EV / LTM Revenue

Annual financials & analyst forecasts

$MCY2021CY2022CY2023CY2024CY2025CY2026ECY2027E
Revenue YoY31%32%57%36%21%19%
Revenue$625M$820M$1.08B$1.70B$2.31B$2.80B$3.33B
Gross Profit$307M$364M$493M$1.02B$1.50B
Gross Profit Margin49.1%44.4%45.5%60.3%64.8%
EBITDA($443M)($507M)($383M)($144M)($215M)($1.05B)($1.25B)
EBITDA Margin-70.9%-61.8%-35.4%-8.5%-9.3%-37.5%-37.5%
EBIT($468M)($541M)($446M)($222M)($310M)($1.12B)($1.33B)
Net Income($472M)($548M)($435M)($190M)($208M)($232M)($26M)
Free Cash Flow($376M)($479M)($286M)$69M$97M
FCF Margin-60.2%-58.4%-26.4%4.1%4.2%
Short-Term Debt$50M$80M$80M$80M$80M
Long-Term Debt$280M$282M$283M$0M$0M
Cash & Cash Equivalents$84M$466M$642M$946M$1.08B
Net Debt$246M($104M)($279M)($865M)($996M)
Net Debt / EBITDA
Rule of 40-27.3%5.6%60.8%40.1%
Figures in $M. True calendar years (Jan–Dec) built from quarterly data — income & cash-flow lines summed across the four quarters, balance sheet as of year-end. E columns are calendarized analyst consensus — gross profit, cash flow and balance-sheet lines are not estimated. Net debt = short-term debt + long-term debt − cash & cash equivalents; Rule of 40 = YoY revenue growth + FCF margin.