Exact Sciences Corporation

EXASUS

Exact Sciences Corporation specializes in developing and distributing cancer screening and diagnostic tools across the United States and internationally. Their key product, Cologuard, is an innovative, non-invasive test that analyzes stool-based DNA to identify specific DNA and hemoglobin biomarkers indicative of colorectal cancer and precancerous conditions. The company's extensive portfolio also includes the Oncotype DX family of gene expression tests, designed for breast, prostate, and colon cancers. Within this suite, the Oncotype Test provides detailed tumor profiling from tissue samples, assisting in treatment selection for individuals battling advanced, metastatic, refractory, or recurrent cancers. Furthermore, they offer the Oncotype DX AR-V7 Nucleus Detect Test, a liquid biopsy designed for advanced-stage prostate cancer patients, and Oncomap ExTra, which delivers a comprehensive biological insight into challenging, rare, or aggressive malignancies. Exact Sciences also provides COVID-19 testing services. Future initiatives involve enhancing Cologuard's performance characteristics and pioneering novel blood- and other fluid-based diagnostic tests. The company maintains important license agreements with the MAYO Foundation for Medical Education and Research and Hologic, Inc. Established in 1995, Exact Sciences Corporation's corporate headquarters are located in Madison, Wisconsin.

Founded1995IPO year2001As of2026-08-04
Market Cap
$20.03B
Enterprise Value
$21.58B
EV / LTM Revenue
6.6x
EV / NTM Revenue
5.4x
Trading multiples

Enterprise value over trailing (LTM) vs. forward (NTM) fundamentals. Click an LTM cell to chart it.

LTM
trailing
NTM
forward
Revenue
5.4x
Gross Profit
7.8x
EBITDA
18.1x
Classification
Sector
Healthcare Services
Sub-sector
Diagnostics & Clinical Services
Listing
EXAS
Country
US
Historical valuation & fundamentals

EV / LTM Revenue

Annual financials & analyst forecasts

$MCY2021CY2022CY2023CY2024CY2025CY2026ECY2027E
Revenue YoY18%20%10%18%14%13%
Revenue$1.77B$2.08B$2.50B$2.76B$3.25B$3.69B$4.18B
Gross Profit$1.31B$1.51B$1.85B$1.86B$2.26B
Gross Profit Margin74.0%72.4%73.8%67.3%69.7%
EBITDA($649M)($420M)$17M($802M)$54M$1.11B$1.25B
EBITDA Margin-36.7%-20.2%0.7%-29.1%1.7%30.0%30.0%
EBIT($856M)($594M)($215M)($1.05B)($200M)$956M$1.08B
Net Income($596M)($624M)($204M)($1.03B)($208M)$36M$206M
Free Cash Flow($180M)($438M)$32M$75M$357M
FCF Margin-10.2%-21.0%1.3%2.7%11.0%
Short-Term Debt$0M$0M$50M$249M$39M
Long-Term Debt$2.18B$2.24B$2.31B$2.32B$2.33B
Cash & Cash Equivalents$315M$242M$605M$601M$956M
Net Debt$1.86B$1.99B$1.76B$1.97B$1.41B
Net Debt / EBITDA104.5x26.0x
Rule of 40-3.1%21.2%13.1%28.7%
Figures in $M. True calendar years (Jan–Dec) built from quarterly data — income & cash-flow lines summed across the four quarters, balance sheet as of year-end. E columns are calendarized analyst consensus — gross profit, cash flow and balance-sheet lines are not estimated. Net debt = short-term debt + long-term debt − cash & cash equivalents; Rule of 40 = YoY revenue growth + FCF margin.